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The Mathieson Chemical Corporation utilized the services of Jonas Kamlet and The Kamlet Laboratories and stood out as one of Kamlet's main clients. Kamlet corresponded with the Mathieson Chemical Corporation regarding topics such as the development of new products and the creation of new processes within the chemical industry, as well as within other related industries.

Jonas Kamlet often contacted potential clients in order to make them aware of new processes, scientific developments, and other pertinent information; for example, if the Kamlet Laboratory had recently developed a better process for manufacturing particular acids, Kamlet might then contacted potential clients about the matter. Some such companies did indeed become clients of Kamlet's at some time or another, such as the Mathieson Chemical Corp., Mathieson Hydrocarbon Chemical Co., Pittsburgh Coke and Chemical Co., Pittsburgh Agricultural Chemical Co., Emery Industries, the Thiokol Corp., the American Potash and Chemical Corp., Tennessee Products and Chemical Corp., B.F. Goodrich Chemical Co., American Home Products Corp., Miles Laboratories, Publicker Industries, Alrose Chemical Co., Gallowhur Chemical Co., Merck & Co., and others. Kamlet also displayed a yen for information pertinent to his own interests; thus, he often wrote requesting information relevant to his scientific work from corporate entities or individuals.

Harry Kamlet was the father of Jonas. The older Kamlet was struck by an automobile in March of 1953, dying approximately one month later. Mortimer J. Kamlet, Jonas' brother, continued with a good deal of his brother's work after the plane crash. Some of Mortimer's personal work centered on topics such as linear solvation energy relationships, solubility, and solvatochromic research. Most of the family's activities were focused in New York.