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Photographs and personal papers, 1828-1931, of the Anderson, Craig, Hargis, Holden, Kryger, McConaughy, and Pape families of Mobile, Alabama; Pensacola, Tallahassee and Deland, Florida. Includes records concerning Dr. Warren E. Anderson and early hospitals in Pensacola including St. Anthony's Sanitarium and the Pensacola Infirmary among others, and early nurses training under F. Elizabeth Crowell.

Publications, photographs, postcards, cigar labels, maps, realia, manuscripts, diaries, printed ephemera, artifacts, and other materials documenting the history of Tampa, Florida and its vicinity, with particular emphasis on the area's Cuban, Spanish, and Italian immigrant communities of Ybor City and West Tampa.

The Arlyn Austin Katims Civil War Collection focuses upon the Civil War from the Union position. Within the collection are illustrations, currency, and a number of artifacts from the era. Items of special interest include an authentic mourning card from Abraham Lincoln's funeral and newspapers reporting Lincoln's death.