Collection
- David Sellers Newspaper Collection, 1837-19031
- Derrick Joshua Beard Collection, Circa 1854-19861
- Diary of a Confederate Officer, 1864-1865, Date acquired: 04/29/19581
- Dime Novels Collection, 1861-1942, bulk 1873-19271
- Directory of the Confederate States, 1861-1865, Date acquired: 02/19/19481
- Dr. Edward Bradford Papers, 1830-18711
- Dr. F. A. Byrd Papers, 1819-1892, Date acquired: 03/22/19681
- Dr. John O'Sullivan Faculty Papers, 1831-1999, bulk 1940-19801
- Dr. Mark F. Boyd Collection, 1516-1965, Date acquired: 04/03/1967, Date acquired: 04/01/19681
- Dr. Walter Wadepuhl Faculty Papers Collection, 1781-19891
- Eartha M. M. White Papers, 1831-19741
- Edith Daly Papers of Eugene Elliott, bulk 1849-19801
- Edward M. Tidball Civil War Papers, 1859-18651
- El Círculo Cubano (Cuban Club) records, 1852-1989, Date acquired: 00/00/2000, bulk 1902-19591
- Elena Kurstin Cuban Memorabilia Collection, date unknown1
- Ella Scoble Opperman Papers, 1719-1963, bulk 1900-19631
- Ellen Peterson Legacy Collection, 1923-20181
- Elliot Cross and James A. Cross Civil War Collection, 1861-2008, bulk 1861-18881
- Ellis Hughes papers, 1813-1866, Date acquired: 00/00/19741
- Escambia County (Florida) Deed Index Books, bulk 1820-19821