Collection
- John and Ellen Sheppard Historical Fort Myers Collection, bulk 1865-2000s2
- Lopez-Portillo y Lancaster-Jones Collection, 1784-20232
- Love-Thornell Collection of Black American Photographs, Circa 1850-19502
- Mostly Florida Broadsides and Ephemera, bulk 1869-19582
- Ramiro Casañas Collection, 1805-20062
- Simmons family papers, 1772-1951, Date acquired: 02/00/19622
- 17th-20th Century Correspondence and Documents, 1664-19761
- 19th c. Florida Letters, 1835-18911
- Allen Forte Treatise Collection, 1715-18941
- Anderson Family Papers, 1828-1931, Date acquired: 08/00/19811
- Anthony P. "Tony" Pizzo collection, 1824-1994, Date acquired: 10/23/19821
- Autograph collection, 1826-1950, Acquired 19741
- Bird and Ulmer Papers, 1851-1922, Date acquired: 10/30/19641
- Book Arts Collection, 1738-20141
- British East, West and Territorial Florida, Georgia, South Carolina, Tennessee and Mississippi Miscellaneous documents, letters, etc., 1773-18681
- Bryan Family Collection, Circa 1800-19591
- Burrow, Dorothy, Papers, 1840-1979, Date acquired: 07/00/19831
- Captain Hugh Black Papers, 1840-1913, Date acquired: 01/30/19641
- Catherine Fitzgerald Parramore gift, 1835-1933, Date acquired: 07/01/19691
- Chandler Holmes Smith Papers, 1844-18861